Description Aspilets 80Mg Tablet Indications / Uses : Primary Prevention of Thromboembolic Disorders and Cardiovascular Events: Ischemic stroke; transient ischemic attack (TIA); prevention of recurrent myocardial infarction (MI); unstable angina pectoris; chronic stable angina pectoris. Secondary Prevention of Cardiovascular Disease in Persons with Diabetes Mellitus Especially in the Following Subgroups: History of MI, vascular bypass procedure, stroke or transient ischemic attack and angina. Persons with additional risk factors: Hypertension, smoking, dyslipidemia and family history of cardiovascular disease. Revascularization Procedures: Patients who have undergone revascularization procedures eg, coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA) and carotid endarterectomy when there is a preexisting condition for which aspirin is already indicated. Pregnancy-Induced Hypertension: Primary prevention of pregnancy-induced hypertension, preeclampsia and intrauterine growth retardation particularly in pregnant women with preexisting chronic hypertension, auto-immune disorders like systemic lupus erythematosus (SLE), positive cardiolipin antibody test, history of recurring toxemia in successive pregnancies, and hypotension developing before the 20th week of gestation. Administration : Should be taken with food: Take immediately after meals w/ a full glass of water unless patient is fluid-restricted. Swallow whole, do not chew/crush/bite the tab. Contraindications : Known hypersensitivity to aspirin or to any of the excipients of Aspilets and Aspilets-EC. Asthma, rhinitis and nasal polyps. Aspirin may cause severe urticaria, angioedema, or bronchospasm. Use in children: Avoid use in children or teenagers for viral infections with or without fever because of the risk of Reye’s syndrome with concomitant use of aspirin in certain viral illnesses. Special Precautions : Gastrointestinal Bleeding: Aspilets/Aspilets-EC contain a nonsteroidal anti-inflammatory drug (NSAID), which may cause severe gastrointestinal bleeding. The chance is higher if: =60 years; had gastrointestinal ulcers or bleeding problems; taking anticoagulant or steroid medicine; taking other medicines containing prescription or nonprescription NSAIDs (ibuprofen, naproxen or others); taking more or for a longer time than prescribed. Alcohol: Patients who consume =3 alcoholic drinks everyday should be counseled about the bleeding risks involved with chronic, heavy alcohol use while taking aspirin. Coagulation Abnormalities: Aspirin can inhibit platelet function leading to an increase in bleeding time. Avoid its use in patients with inherited (hemophilia) or acquired (liver disease or vitamin K deficiency) bleeding disorders. General: Do not use in patients with severe renal failure [glomerular filtration rate (GFR) >10 mL/min] and severe hepatic insufficiency. Avoid aspirin use 1 week prior to and during labor, delivery and any surgical procedure because it can result in excessive blood loss.
